


#Surgical hand asepsis skin#
The 5 main products currently marketed for preoperative antisepsis are alcohol, chlorhexidine, iodine/iodophors, parachlorometaxylenol (PCMX), and triclosan, with povidone iodine (PVI) and chlorhexidine gluconate (CHG) the most commonly used for skin preparations. Surgical hand antisepsis is also essential for preventing chronic infections associated with contaminated implants. The risk of glove defects is related to the type of surgery, ranging from 7% in urologic surgery to 65% in cardiothoracic surgery. However, undetected perforations of surgical gloves are common and increase in frequency with duration of glove wear. Intact surgical gloves are the most important barrier to the bi-directional migration of micro-organisms between the hands of surgical team members and the patient. Surgical hand antisepsis has long been used to prevent SSI. Surgical site infections (SSI) are among the most common hospital-acquired infections worldwide despite significant developments in surgical technique.
#Surgical hand asepsis trial#
The trial was registered at (ID: NCT02500758). Fingernails should be a particular focus of antisepsis in preparation for surgery. Conclusions:Ĭhlorhexidine digluconate 4% and PCMX 3% had similar bactericidal efficacy, but they failed to meet the EN 12791 efficacy standard. Fingernails had greater bacterial loads than skin on the fingertips. Chlorhexidine digluconate 4% and PCMX 3% increased bacterial load on the fingertips after participants had worn gloves for 3 hours. The bactericidal performances of chlorhexidine digluconate 4% and PCMX 3% did not differ significantly. Results:Ĭhlorhexidine digluconate 4% and PCMX 3% did not decrease bacterial load on the hands. Our procedures followed those specified by European Norm (EN) 12791 for evaluating surgical hand antiseptics and using cotton swab for fingertips and fingernails. We assessed bacterial load after a prewash with soft soap, immediately after application of an antiseptic, and 3 hours after application and wearing of sterile, powder-free gloves. We conducted a randomized, double-blind, controlled crossover trial to compare the bacterial loads on fingertips and fingernails under laboratory conditions after use of antiseptic test products, including chlorhexidine digluconate 4%, PCMX 3%, and a reference solution of propan-1-ol 60% (P-1). To our knowledge, PCMX has not been evaluated for bactericidal efficacy “in vivo. Chlorhexidine and parachlorometaxylenol (PCMX) are antiseptics recommended for surgical hand antisepsis.
